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1

Similarity and dissimilarity in the stereogeometry of the active sites of thrombin, trypsin, plasmin and glandular kallikrein

Akiko Hijikata-Okunomiya, Shosuke Okamoto, Ryoji Kikumoto, Yoshikuni Tamao, Kazuo Ohkubo, Tohru Tezuka, Shinji Tonomura, Osamu Matsumoto

Journal:

Thrombosis Research

Année:

1987

Langue:

english

Fichier:

PDF, 859 KB

english, 1987

2

Characterization and Bone Response of Carbonate-Containing Apatite-Coated Titanium Implants Using an Aqueous Spray Coating

Yagi, Ryo, Mochizuki, Chihiro, Sato, Mitsunobu, Toyama, Takeshi, Hirota, Masatsugu, Hayakawa, Tohru, Ohkubo, Chikahiro

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 25.57 MB

english, 2017

3

Dissociation between the mitogenic effect and antitumor activity of seed extract from Aeginetia indica L.

Jian-Guo Chai, Masato Okamoto, Takashi Bando, Hideyuki Nagasawa, Hajime Hisaeda, Tohru Sakai, Kunisuke Himeno, Mitsunobu Sato, Shinya Ohkubo

Journal:

Immunopharmacology

Année:

1995

Langue:

english

Fichier:

PDF, 559 KB

english, 1995

4

Spatial distribution of radionuclides produced in copper by photonuclear spallation reactions

Takashi Nakamura, Tohru Ohkubo, Yoshimoto Uwamino

Journal:

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

Année:

1987

Langue:

english

Fichier:

PDF, 494 KB

english, 1987

5

Establishment of a simple neutron calibration field using a moderated 252Cf source: Part II. Experimental characterization of simple neutron calibration field

Satoshi Iwai, Tohru Ohkubo, Akihisa Hara, Takashi Nakamura

Journal:

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

Année:

1987

Langue:

english

Fichier:

PDF, 873 KB

english, 1987

6

Heteroepitaxial growth of InN on Si(111) using a GaAs intermediate layer

Akio Yamamoto, Yasuyuki Yamauchi, Mitsugu Ohkubo, Akihiro Hashimoto, Tohru Saitoh

Journal:

Solid-State Electronics

Année:

1997

Langue:

english

Fichier:

PDF, 387 KB

english, 1997

7

Growth factor for cardiac hypertrophy

Makoto Nagano, Tadanari Ohkubo, Tohru Arino, Masahito Tsuchiya, Makoto Nagai

Journal:

Molecular and Cellular Biochemistry

Année:

1993

Langue:

english

Fichier:

PDF, 707 KB

english, 1993

8

Novel mutations in the cytochrome P450 2C19 gene: a pitfall of the PCR-RFLP method for identifying a common mutation

Yumiko Ohkubo, Akihito Ueta, Naoki Ando, Tetsuya Ito, Sachiko Yamaguchi, Kantaro Mizuno, Satoshi Sumi, Tohru Maeda, Daiju Yamazaki, Yukihisa Kurono, Shinji Fujimoto, Hajime Togari

Journal:

Journal of Human Genetics

Année:

2006

Langue:

english

Fichier:

PDF, 276 KB

english, 2006

9

A Cooperative Randomized Study on Tegafur plus Mitomycin C versus Combined Tegafur and Uracil plus Mitomycin C in the Treatment of Advanced Gastric Cancer

Minoru Kurihara, Tuguhiko Izumi, Shigeaki Yoshida, Toshiharu Ohkubo, Shoji Suga, Atsushi Kiyohashi, Tohru Yaosaka, Hiromu Takahashi, Tetsuo Ito, Tadashi Sasai, Toshikazu Akiya, Shugo Akazawa, Takashi

Journal:

Année:

1991

Fichier:

PDF, 414 KB

1991

10

Lack of genetic association between cholesteryl ester transfer protein and Japanese sporadic Alzheimer’s disease

Akiyoshi KITAJIMA, Nobuto SHIBATA, Tohru OHNUMA, Shinji HIGASHI, Taku OHKUBO, Chie USUI, Tomoko WATANABE, Ritsuko KAWASHIMA, Mieko OHTSUKA, Akira UEKI, Masatsugu NAGAO, Heii ARAI

Journal:

Psychogeriatrics

Année:

2006

Langue:

english

Fichier:

PDF, 93 KB

english, 2006

11

Depression of mitochondrial metabolism by downregulation of cytoplasmic deacetylase, HDAC6

Kazuo Kamemura, Mitsutaka Ogawa, Saki Ohkubo, Yasuhiro Ohtsuka, Yu Shitara, Tohru Komiya, Satoko Maeda, Akihiro Ito, Minoru Yoshida

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 409 KB

english, 2012

12

Spatial distribution of the basidiocarps of aphyllophoraceous fungi in a tropical rainforest on Borneo Island, Malaysia

Satoshi Yamashita, Tsutomu Hattori, Tatsuhiro Ohkubo, Tohru Nakashizuka

Journal:

Mycological Research

Année:

2009

Langue:

english

Fichier:

PDF, 479 KB

english, 2009

13

Appearances and chronological changes of mummichog Fundulus heteroclitus FSH cells and LH cells during ontogeny, sexual differentiation, and gonadal development

Akio Shimizu, Masami Hamaguchi, Haruka Ito, Makoto Ohkubo, Miho Udagawa, Kazunori Fujii, Tohru Kobayashi, Masaru Nakamura

Journal:

General and Comparative Endocrinology

Année:

2008

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2008

14

Effects of long-term treatment with antihypertensive drugs on myocardium in SHR

Nobuakira Takeda, Tohru Arino, Akira Tanamura, Takaaki Iwai, Izuru Nakamura, Mitsutoshi Kato, Tadanari Ohkubo, Makoto Nagano

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1992

Langue:

english

Fichier:

PDF, 103 KB

english, 1992

15

Cardiac growth factor and chalone in cardiac hypertrophy

Makoto Nagano, Makoto Nagai, Tohru Arino, Masahito Tsuchiya, Tadanari Ohkubo

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1992

Langue:

english

Fichier:

PDF, 100 KB

english, 1992

16

Myocardial elasticity in pressure-overloaded cardiac hypertrophy

Akira Tanamura, Masahito Tsuchiya, Tohru Arino, Takaaki Iwai, Izuru Nakamura, Tadanari Ohkubo, Nobuakira Takeda, Makoto Nagano

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1992

Langue:

english

Fichier:

PDF, 98 KB

english, 1992

17

Regression of cardiac hypertrophy in hypertensive rats

Takaaki Iwai, Masahito Tsuchiya, Tohru Arino, Akira Tanamura, Izuru Nakamura, Tadanari Ohkubo, Nobuakira Takeda, Makoto Nagano

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1992

Langue:

english

Fichier:

PDF, 98 KB

english, 1992

18

Cardiac growth factor and chalone in cardiac hypertrophy

Makoto Nagano, Tadanari Ohkubo, Makoto Nagai, Tohru Arino, Masahito Tsuchiya

Journal:

Journal of Molecular and Cellular Cardiology

Année:

1992

Langue:

english

Fichier:

PDF, 103 KB

english, 1992

19

Identification of antigenic epitopes recognized by Mac-2 binding protein-specific cytotoxic T lymphocytes for use in cancer immunotherapy

Yoshitomo Ozaki, Keiichi Kontani, Koji Teramoto, Takuya Fujita, Noriaki Tezuka, Satoru Sawai, Hiroyoshi Watanabe, Shozo Fujino, Tohru Asai, Iwao Ohkubo

Journal:

Biochemical and Biophysical Research Communications

Année:

2004

Langue:

english

Fichier:

PDF, 229 KB

english, 2004

20

Genetic association between matrix metalloproteinase MMP-9 and MMP-3 polymorphisms and Japanese sporadic Alzheimer's disease

Nobuto Shibata, Tohru Ohnuma, Shinji Higashi, Chie Usui, Taku Ohkubo, Akiyoshi Kitajima, Akira Ueki, Masatsugu Nagao, Heii Arai

Journal:

Neurobiology of Aging

Année:

2005

Langue:

english

Fichier:

PDF, 60 KB

english, 2005

21

Increased plasma glutamate by antipsychotic medication and its relationship to glutaminase 1 and 2 genotypes in schizophrenia — Juntendo University Schizophrenia Projects (JUSP)

Hitoshi Maeshima, Tohru Ohnuma, Yoshie Sakai, Nobuto Shibata, Hajime Baba, Hiroshi Ihara, Maiko Higashi, Taku Ohkubo, Eiko Nozawa, Sawako Abe, Aya Ichikawa, Yoshiyuki Nakano, Yushi Utsumi, Toshihito S

Journal:

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Année:

2007

Langue:

english

Fichier:

PDF, 419 KB

english, 2007

22

Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency in the Japanese population

Tohru Maeda, Satoshi Sumi, Akihito Ueta, Yumiko Ohkubo, Tetsuya Ito, Anthony M. Marinaki, Yukihisa Kurono, Shinsaku Hasegawa, Hajime Togari

Journal:

Molecular Genetics and Metabolism

Année:

2005

Langue:

english

Fichier:

PDF, 596 KB

english, 2005

23

Genotypes of the βENaC gene have little influence on blood pressure level in the Japanese population

Mitsunobu Matsubara, Hirohito Metoki, Michiko Suzuki, Tohru Fujiwara, Masahiro Kikuya, Mari Michimata, Takayoshi Ohkubo, Atsushi Hozawa, Ichiro Tsuji, Shigeru Hisamichi, Tsutomu Araki, Yutaka Imai

Journal:

American Journal of Hypertension

Année:

2002

Langue:

english

Fichier:

PDF, 94 KB

english, 2002

24

T+31C polymorphism of angiotensinogen gene and nocturnal blood pressure decline: the Ohasama study

Tohru Fujiwara, Tomohiro Katsuya, Mitsunobu Matsubara, Tadayoshi Mikami, Kazuhiko Ishikawa, Masahiro Kikuya, Takayoshi Ohkubo, Atsushi Hozawa, Mari Michimata, Michiko Suzuki, Hirohito Metoki, Kei Asay

Journal:

American Journal of Hypertension

Année:

2002

Langue:

english

Fichier:

PDF, 73 KB

english, 2002

25

P1-294: Genetic association between PCSK9 and USF1 polymorphisms and Japanese Alzheimer’s disease and plasma cholesterol level

Nobuto Shibata, Tohru Ohnuma, Chie Usui, Taku Ohkubo, Tomoko Watanabe, Ritsuko Kawashima, Akiyoshi Kitajima, Koichi Miyakawa, Akira Ueki, Heii Arai

Journal:

Alzheimer's & Dementia

Année:

2006

Langue:

english

Fichier:

PDF, 56 KB

english, 2006

26

Thrombin inhibitors. 3. Carboxyl-containing amide derivatives of N.alpha.-substituted L-arginine

Kikumoto, Ryoji, Tamao, Yoshikuni, Ohkubo, Kazuo, Tezuka, Tohru, Tonomura, Shinji, Okamoto, Shosuke, Hijikata, Akiko

Journal:

Journal of Medicinal Chemistry

Année:

1980

Langue:

english

Fichier:

PDF, 727 KB

english, 1980

27

No Genetic Association between the Myeloperoxidase Gene –463 Polymorphism and Estrogen Receptor-α Gene Polymorphisms and Japanese Sporadic Alzheimer’s Disease

Usui, Chie, Shibata, Nobuto, Ohnuma, Tohru, Higashi, Shinji, Ohkubo, Taku, Ueki, Akira, Nagao, Masatsugu, Arai, Heii

Journal:

Dementia and Geriatric Cognitive Disorders

Année:

2006

Langue:

english

Fichier:

PDF, 105 KB

english, 2006

28

Thrombin inhibitors. 2. Amide derivatives of N.alpha.-substituted L-arginine

Kikumoto, Ryoji, Tamao, Yoshikuni, Ohkubo, Kazuo, Tezuka, Tohru, Tonomura, Shinji, Okamoto, Shosuke, Funahara, Yoshinori, Hijikata, Akiko

Journal:

Journal of Medicinal Chemistry

Année:

1980

Langue:

english

Fichier:

PDF, 670 KB

english, 1980

29

Access to a novel near-infrared photodynamic therapy through the combined use of 5-aminolevulinic acid and lanthanide nanoparticles

Shimoyama, Atsushi, Watase, Hiroya, Liu, Yu, Ogura, Shun-Ichiro, Hagiya, Yuichiro, Takahashi, Kiwamu, Inoue, Katsushi, Tanaka, Tohru, Murayama, Yasutoshi, Otsuji, Eigo, Ohkubo, Akihiro, Yuasa, Hideya

Journal:

Photodiagnosis and Photodynamic Therapy

Année:

2013

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2013

30

Fatigue resistance and retentive force of cast clasps treated by shot peening

Tokue, Ai, Hayakawa, Tohru, Ohkubo, Chikahiro

Journal:

Journal of Prosthodontic Research

Année:

2013

Langue:

english

Fichier:

PDF, 1.52 MB

english, 2013

31

Bone responses to zirconia implants with a thin carbonate-containing hydroxyapatite coating using a molecular precursor method

Hirota, Masatsugu, Hayakawa, Tohru, Ohkubo, Chikahiro, Sato, Mitsunobu, Hara, Hiroki, Toyama, Takeshi, Tanaka, Yasuhiro

Journal:

Journal of Biomedical Materials Research Part B: Applied Biomaterials

Année:

2014

Langue:

english

Fichier:

PDF, 1.12 MB

english, 2014

32

Regeneration and development in beech-dwarf bamboo forest in Japan

Peters, Rob, Nakashizuka, Tohru, Ohkubo, Tatsuhiro

Journal:

Forest Ecology and Management

Année:

1992

Langue:

english

Fichier:

PDF, 1013 KB

english, 1992

33

SCN5A mutation associated with ventricular fibrillation, early repolarization, and concealed myocardial abnormalities

Watanabe, Hiroshi, Ohkubo, Kimie, Watanabe, Ichiro, Matsuyama, Taka-aki, Ishibashi-Ueda, Hatsue, Yagihara, Nobue, Shimizu, Wataru, Horie, Minoru, Minamino, Tohru, Makita, Naomasa

Journal:

International Journal of Cardiology

Année:

2013

Langue:

english

Fichier:

PDF, 808 KB

english, 2013

34

Subcellular localization of rat Isk protein in renal tubular cells: An electron microscopic immunohistochemical study using anti-peptide antibodies

Sugimoto, Tetsuo, Ueyama, Teizo, Houtani, Takeshi, Ikeda, Michiko, Ohkubo, Hiroaki, Takumi, Tohru, Tanabe, Yasuto, Nakanishi, Shigetada

Journal:

Neuroscience Research Supplements

Année:

1991

Langue:

english

Fichier:

PDF, 85 KB

english, 1991

35

Amino Acid Sequence of Mammalian Elongation Factor 2 Deduced from the cDNA Sequence: Homology with GTP-Binding Proteins

Kenji Kohno, Tsuyoshi Uchida, Hiroaki Ohkubo, Shigetada Nakanishi, Tohru Nakanishi, Toshikazu Fukui, Eiko Ohtsuka, Morio Ikehara and Yoshio Okada

Journal:

Proceedings of the National Academy of Sciences

Année:

1986

Langue:

english

Fichier:

PDF, 905 KB

english, 1986

36

Photoinduced enantioselective and catalytic reduction of tris(acetylacetonato)cobalt with a chiral ruthenium photosensitizer

Ohkubo, Katsutoshi, Hamada, Taisuke, Inaoka, Tohru, Ishida, Hitoshi

Journal:

Inorganic Chemistry

Année:

1989

Langue:

english

Fichier:

PDF, 281 KB

english, 1989

37

Ligand effects of ruthenium 2,2?-bipyridine and 1,10-phenanthroline complexes on the electrochemical reduction of CO2

Ishida, Hitoshi, Fujiki, Katsuyuki, Ohba, Tomoyuki, Ohkubo, Katsutoshi, Tanaka, Koji, Terada, Tohru, Tanaka, Toshio

Journal:

Journal of the Chemical Society Dalton Transactions

Année:

1990

Langue:

english

Fichier:

PDF, 708 KB

english, 1990

38

Study Design of HOMED-BP: Hypertension Objective Treatment Based on Measurement by Electrical Devices of Blood Pressure

Fujiwara, Tohru, Matsubara, Mitsunobu, Ohkubo, Takayoshi, Imai, Yutaka

Journal:

Clinical and Experimental Hypertension

Année:

2003

Langue:

english

Fichier:

PDF, 40 KB

english, 2003

39

Dual species ion implantation in GaAs

Inada, Taroh, Kato, Shigeki, Ohkubo, Tatsuya, Hara, Tohru

Journal:

Radiation Effects

Année:

1980

Langue:

english

Fichier:

PDF, 403 KB

english, 1980

40

Microstructure Analysis of Polyacetal: Free-Volume Study by Positronium Lifetime Measurement

Ito, Kenji, Nanasawa, Atsushi, Tanimura, Noritaka, Li, Hong Ling, Ohkubo, Tohru, Ujihira, Yusuke, Nomura, Kiyoshi

Journal:

Materials Science Forum

Année:

2001

Fichier:

PDF, 252 KB

2001

41

No Genetic Association between ATP Binding Cassette Proteins and Japanese Sporadic Alzheimer’s Disease

Ohkubo, Taku, Shibata, Nobuto, Ohnuma, Tohru, Higashi, Shinji, Usui, Chie, Ueki, Akira, Nagao, Masatsugu, Arai, Heii

Journal:

Dementia and Geriatric Cognitive Disorders

Année:

2005

Langue:

english

Fichier:

PDF, 82 KB

english, 2005

42

Measurements of the Production Cross Sections of Tritium from Oxygen Using p-Be and p-Li Neutrons up to En = 38 MeV

Shibata, Seiichi, Shibata, Tokushi, Imamura, Mineo, Ohkubo, Tohru, Satoh, Shingo, Uwamino, Yoshitomo, Morikawa, Naotake, Nogawa, Norio

Journal:

Radiochimica Acta

Année:

1996

Langue:

english

Fichier:

PDF, 562 KB

english, 1996

43

Primary empty sella in association with superior sagittal sinus thrombosis and dural arteriovenous malformation

Haisa, Toshihiko, Yoshida, Shinichi, Ohkubo, Toshiyuki, Yoshikawa, Kohki, Machida, Tohru

Journal:

Journal of Neurosurgery

Année:

1994

Fichier:

PDF, 431 KB

1994

44

Mononuclear Phagocytes: A Major Population of Effector Cells Responsible for Rejection of Allografted Tumor Cells in Mice

Ryotaro Yoshida, Osamu Takikawa, Tohru Oku and Akemi Habara-Ohkubo

Journal:

Proceedings of the National Academy of Sciences

Année:

1991

Langue:

english

Fichier:

PDF, 1.44 MB

english, 1991

45

INSUFFICIENT DURATION OF ACTION OF ANTIHYPERTENSIVE DRUGS MEDIATES HIGH BLOOD PRESSURE IN THE MORNINGIN HYPERTENSIVE POPULATION:THE OHASAMA STUDY

Chonan, Kenichi, Hashimoto, Junichiro, Ohkubo, Takayoshi, Tsuji, Ichiro, Nagai, Kenichi, Kikuya, Masahiro, Hozawa, Atsushi, Matsubara, Mitsunobu, Suzuki, Michiko, Fujiwara, Tohru, Araki, Tsutomu, Sato

Journal:

Clinical and Experimental Hypertension

Année:

2002

Langue:

english

Fichier:

PDF, 291 KB

english, 2002

46

Enhanced Production of Interferon-gamma as a Possible Cause of Protein-losing Enteropathy After Modified Fontan Operation

Shimizu, Toshiaki, Nagata, Satoru, Fujii, Tohru, Takahashi, Ken, Kishiro, Masahiko, Ohkubo, Mataichi, Akimoto, Katsumi, Yamashiro, Yuichiro

Journal:

Journal of Pediatric Gastroenterology & Nutrition

Année:

2003

Langue:

english

Fichier:

PDF, 575 KB

english, 2003

47

Impact of severe drought associated with the 1997–1998 El Niño in a tropical forest in Sarawak

Nakagawa, Michiko, Tanaka, Kenta, Nakashizuka, Tohru, Ohkubo, Tatsuhiro, Kato, Tsuyoshi, Maeda, Teizou, Sato, Kaori, Miguchi, Hideo, Nagamasu, Hidetoshi, Ogino, Kazuhiko, Teo, Stephen, Hamid, Abang Ab

Journal:

Journal of Tropical Ecology

Année:

2000

Langue:

english

Fichier:

PDF, 182 KB

english, 2000

48

Fecal ??1-Antitrypsin Concentrations as a Measure of Enteric Protein Loss After Modified Fontan Operations

Fujii, Tohru, Shimizu, Toshiaki, Takahashi, Ken, Kishiro, Masahiko, Ohkubo, Mataichi, Akimoto, Katsumi, Yamashiro, Yuichiro

Journal:

Journal of Pediatric Gastroenterology & Nutrition

Année:

2003

Langue:

english

Fichier:

PDF, 209 KB

english, 2003

49

Device for the self-measurement of blood pressure that can monitor blood pressure during sleep

Chonan, Kenichi, Kikuya, Masahiro, Araki, Tsutomu, Fujiwara, Tohru, Suzuki, Michiko, Michimata, Mari, Hashimoto, Junichiro, Ohkubo, Takayoshi, Hozawa, Atsushi, Yamamoto, Norihito, Miyawaki, Yoshinori,

Journal:

Blood Pressure Monitoring

Année:

2001

Langue:

english

Fichier:

PDF, 54 KB

english, 2001

50

Predictive values of automated blood pressure measurement: what can we learn from the Japanese population – the Ohasama study

Imai, Yutaka, Hozawa, Atsushi, Ohkubo, Takayoshi, Tsuji, Ichiro, Yamaguchi, Junko, Matsubara, Mitsunobu, Michimata, Mari, Hashimoto, Junichiro, Fujiwara, Tohru, Nagai, Kenichi, Kitaoka, Hirofumi, Sato

Journal:

Blood Pressure Monitoring

Année:

2001

Langue:

english

Fichier:

PDF, 84 KB

english, 2001